Today, more people are living with chronic illnesses and the adverse symptoms that result from them. New advances in genomics and other fields have allowed scientists to better understand the symptoms of chronic illness, such as pain, fatigue, and disordered sleep. NINR supports research to develop improved, personalized strategies to treat and prevent the adverse symptoms of illness across diverse populations and settings. With support from the NIH, new tools are being developed to assess symptoms and health-related quality of life.