They
analyzed six studies conducted with Gaio involving 425 subjects of both genders
and different initial cholesterol levels, concluding that five studies showed a small
beneficial short-term effect of 6 to 10% on serum LDL cholesterol (Sarkisov et al.,49
Agerbaek et al.,50 Richelsen et al.,52 Bertolami et al.,54 Agerholm-Larsen et al.55).
However, the long-term effect was inconclusive (Richelsen et al.52), and one study
failed to demonstrate any effect at all (Sessions et al.59).