Based on several studies among bacteria, the actionmycetes are noteworthy as antibiotic producers, making three quarters of all known products; the Streptomyces are especially prolific . A search of the recent literature revealed that at least 4,607 patents have been issued on actinomycete related product and processes. Streptomyces covers around 80% of total antibiotic product, with other genera trailing numerically; Micromonospora is the runner up with less than one-tenth as many as Streptomyces. If we include secondary metabolites with biological activities other than antimicrobial, actinomycetes are still be out in front