All these three cassava cellulose bioprocessing scenarios worked for increasing the ethanol yield from the cassava residues. The question is to select the most proper method from the viewpoint of process economy and easy technical handling: could the cellulose ethanol produced be able to balance the increased cost of energy and enzyme usage? However, the previous studies were carried out in individual cases with different cassava residue feedstocks, different enzymes and fermentation strains used, and even in different fermentation and analysis methods. Therefore, these results could not be used for evaluation of cassava cellulose utilization performance and give a convincible conclusion for lack of same comparisons basis.