: Myelosuppression (monitor CBC). May cause platelet dysfunction & hemorrhage; caution in patients taking anticoagulants or antiplatelets. Fluid retention. QT prolongation, caution in patients w/ hypokalemia or hypomagnesemia, congenital long QT syndrome, concomitant antiarrhythmics or QT-prolonging drugs & cumulative high-dose anthracycline therapy. Patients w/ risk factors or history of cardiac disease. Discontinue in case of pulmonary arterial HTN (PAH). Pregnancy