Finding
Table 1 shows the results on antioedematous effect of intraperitoneally administered Bergamot oil on carrageenan paw oedema in rats. At doses of 0.025, 0.05 and 0.100 mL/kg BO caused a significant reduction in paw oedema (27.56%, 30.77% and 63.93%, respectively). In this model, indomethacin, a commonly used anti-inflammatory drug, produced a significant inhibition by 95.70%. As seen in Table 1, all doses of BO showed anti-inflamatory activity higher than that of the control groups, but it was not as strong as indomethacin. Anti-inflammatory activity of 0.100 mL/kg BO was stronger than those of 0.025 and 0.05 mL/kg BO.