We attempted to identify all published and unpublished randomized controlled studies that assessed the management of warfarin therapy in patients undergoing elective dental procedures. We searched MEDLINE and EMBASE databases (1990 to June 2008), and the Cochrane Central Register of Controlled Trials (from its inception to June 2008). We also searched for relevant abstracts from the electronic database of the proceedings of the International Association for Dental Research (from its inception to 2008). We supplemented the search strategy (Appendix 1) by manually reviewing the reference lists of the articles retrieved and by contacting content experts.