Alignment
Bony alignment contributes directly to the force and strain on the knee compartment, ligaments, and musculotendinous structures. Therefore, anatomic gender differences are especially significant about the knee. In addition to the previously mentioned greater genu valgum, females often have increased femoral anterversion, less development of the vastus medialis obliquus (VMO), greater flexibility, and differences in femoral notch shape and width compared to males.