Saccharin (1, 2-benzisothiazol-3(2H)-one-1, 1-dioxide),
(Figure 4) is a non-glucose, low-calorie sugar substitute.
It is found to be new cutting agent added in bulk or as
diluent in illicit drugs because of its easy availability and
low cost. Earlier in a study it was reported as diluent in
illicit cocaine samples (Fucci & De Giovanni 1998).
But in some recent cases saccharin was found in illicit
methaqualone samples along with paracetamol and
phenacetin.