b | Many bacteriocins that inhibit Gram-negative bacteria (and thus need to be transported through the outer and, in many cases, inner membranes before functioning) control their target bacteria by interfering with DNA, RNA and protein metabolism. For example, microcin B17 (MccB17) inhibits DNA gyrase, MccJ25 inhibits RNA polymerase, and MccC7-C51 inhibits aspartyl-tRNA synthatase. There are also exceptions, such as MccE492, that function through pore formation.
b | Many bacteriocins that inhibit Gram-negative bacteria (and thus need to be transported through the outer and, in many cases, inner membranes before functioning) control their target bacteria by interfering with DNA, RNA and protein metabolism. For example, microcin B17 (MccB17) inhibits DNA gyrase, MccJ25 inhibits RNA polymerase, and MccC7-C51 inhibits aspartyl-tRNA synthatase. There are also exceptions, such as MccE492, that function through pore formation.
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