CONCLUSIONS
The UF was successfully employed for separating ACE inhibitory
peptides of tilapia protein hydrolysate. The membrane with
MWCO of 1 kDa was found to be the most suitable for separating
ACE inhibitory peptides since its permeate gave the highest ACE
inhibitory activity. The permeate flux and ability in separation
of peptides with ACE inhibitory activity tended to increase with
TMP and CFV. The gas–liquid two-phase flow could be applied
to enhance the permeate flux and ACE inhibitory peptides separation.
Moreover, appropriate N′
s increases the efficiency of
separation and reduces membrane fouling. Therefore, gas–liquid
two-phase flowwas a beneficial technique for application in bioactive
compound separation by ultra-filtration that can lead to the
development of strategic partnerships with industry in the future.
ACKNOWLEDGEMENTS
This work was financially supported by the Research Grant of
Burapha University through National Research Council of Thailand
(Grant no. 1/2558 and Grant no. 37/2559).