The isolation of the powerful opioid, morphine, in 1804 paved the way for the invention of many modern-day medicines. Morphine was first commercially sold in 1827 by a company called Merck, but was not widely used until the hypodermic needle was invented in 1857 [13]. The future powerhouse Pfizer came into existence in 1849, starting in New York City and erupting to the forefront with the discovery of the antiparasitic santonin [12]. These findings, which are still widely applicable today, took the pharmaceutical industry to a new level, setting the stage for an explosion of industrial advancement brought on by World War I.