a Net reclassification improvement ascertained whether reclassification assigned participantswho
did suffer mortality events to a higher risk category and those did not suffer
events to a lower category, and computed the differences in the proportions of participants,
moving up and down for events and non-events.
b All-cause mortality index,−0.09% [−4 of 4443 participants] for participants without
events and 0.30% [1 of 331 participants] with events, and 0.39% overall (p-value = 0.79).
c Cardiovascularmortality index, 0.15% [7 of 4672 participants] without events, 9.8% [10
of 102 participants] with events, and 9.70% overall (p-value = 0.0086).