Results: In a hypothetical group of 1000 individuals, routine use of iv PPI prevented 40 rebleeds, 9 surgical procedures, and 223 hospital days, and led to incremental
savings of $920 per subject. Probabilistic sensitivity analyses indicated that the strategy of using iv PPI was likely
to be dominant even when accounting for uncertainty.
Conclusions: Based on available evidence, routine administration of iv PPI to all persons presenting with UGI
bleeding represents good value for money and merits consideration as standard hospital policy.