Systemic lupus erythematosus is known as a "chronic cancer" in the private world. It is a worldwide medical problem. It is a common autoimmune inflammatory disease characterized by multiple systemic damage with multiple autoantibodies. The domestic incidence rate is 0.4% - 0.8%. It is more common in women of childbearing age, and children and the elderly can also develop symptoms. The core of its pathogenesis is due to defects and collapse of autoimmune tolerance, limited apoptosis mechanism, leading to disorder of immune regulation, producing a large number of autoantibodies, especially antinuclear antibodies, causing immune complex deposition and cell damage. As a result, chronic inflammatory progressive aggravation of multiple systemic multiple organs can cause considerable mortality and disability.