The potencies of the equimolar single agent solutions composed
of the aromatic (MA) and terpenoid (PUL) were similar.
However, the potency of a 1:1 equimolar mixture of the two agents
was lower than was observed for PUL, but not for MA (Fig. 2A).
The reason the rightward shift of the concentration-response curve
of the mixture was different from that of PUL but not MA was due
to the smaller error associated with the inflection for the former
(Table 1). The potencies of the aromatic benzoate structures, MA,
M2MOB, and their mixture were similar (Fig. 3A, Table 1), as
were the potencies of the aromatic acetophenone structures, OAP,
2MAP and a 1:1 mixture of the two (Fig. 4A). OAP was more
potent than equimolar solutions of MA and the MA/OAP mixture.
There was no difference between the potencies of equimolar
solutions of MA and the MA/OAP mixture (Fig. 5A).
The potencies of the equimolar single agent solutions composedof the aromatic (MA) and terpenoid (PUL) were similar.However, the potency of a 1:1 equimolar mixture of the two agentswas lower than was observed for PUL, but not for MA (Fig. 2A).The reason the rightward shift of the concentration-response curveof the mixture was different from that of PUL but not MA was dueto the smaller error associated with the inflection for the former(Table 1). The potencies of the aromatic benzoate structures, MA,M2MOB, and their mixture were similar (Fig. 3A, Table 1), aswere the potencies of the aromatic acetophenone structures, OAP,2MAP and a 1:1 mixture of the two (Fig. 4A). OAP was morepotent than equimolar solutions of MA and the MA/OAP mixture.There was no difference between the potencies of equimolarsolutions of MA and the MA/OAP mixture (Fig. 5A).
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