Consideration should be given to making cysticercosis a nationally notifiable disease. Currently, only 2 states, California and Oregon, require reporting of cysticercosis. In collaboration with the Centers for Disease Control and Prevention, the Department of Public Health in Los Angeles County is conducting modified active surveillance that includes education of local providers and routine contact with key health care facilities that treat large numbers of cysticercosis cases. When a case is reported, public health nurses initiate an investigation and follow-up that includes obtaining a finger-stick specimen for serologic testing on all close contacts to identify a possible source of infection. When found, persons harboring a T. solium tapeworm are treated to prevent possible ongoing transmission. With heightened awareness, improved surveillance, reporting, and follow-up, cysticercosis transmission in the United States can be prevented and the infection’s effects on public health can be reduced.