Heretofore, to our knowledge, no comprehensive report or information is available on lead, cadmium, copper and zinc concentrations of fish from the Persian Gulf with regard to the seasonal or habitat variations. Also, our previous results on total arsenic and mercury supported the influence of season and habitat parameters on their concentrations [22]. Different seasonal dependent conditions such as water temperature, dietary factors and growth and reproductive cycles are effective on heavy metal fluctuations [23] and [24]. The higher metal content in winter might be a result from considerable rainfall which washed down the wastes [22] and [25]. Table 5 shows the highest and the lowest concentration of lead in A. latus (0.534 ± 0.102 μg/g) and T. ilisha (0.046 ± 0.009 μg/g) in winter, respectively.