ransport Minister Francisco Garces said the short-haul airliner crashed at about 1000 local time (1430 GMT), some 10km (six miles) from Puerto Ordaz, a suburb of Ciudad Guayana where the airport is located.
The plane went down on wasteland owned by the state-run Sidor steel mill, he added.
Mr Gomez said the area was used to store barrels of material used in the steel industry, and that no Sidor workers had been hurt. The mill has since been evacuated.
In the last major air crash in Venezuela in 2008, a plane crashed into the Andes mountains in the west of the country, killing all 46 people on board.