You and your doctor should choose an ACEI based primarily on its record in reducing heart attacks, strokes, and preventing the progression of heart disease and failure, coronary artery disease, and kidney disease. Where the evidence is equivocal, cost may be a deciding factor, especially if you do not have drug coverage under a health insurance plan. The monthly cost of ACEIs varies from $10 or less to about $50 for most generics to more than $100 for some brand-name versions..