Guiding framework
Our goal is to develop and evaluate a theory-based, knowledge translation intervention to provide practical guidance about how to improve physician hand hygiene compliance. However, the development and evaluation of complex interventions such as knowledge translation interventions raise specific methodological and conceptual challenges. We have therefore adopted the UK Medical Research Council Complex Interventions Framework (MRC Framework) [39,40], which provides an iterative phased approach to the development and evaluation of complex interventions. The MRC framework suggests that the evaluation of complex interventions should follow a sequential approach, involving: