recordings of the severity of nausea were made twice
daily in the morning and evening. The average daily
nausea scores were calculated. The frequency of
vomiting was recorded daily. The change in nausea
score and frequency of vomiting in both group were
compared. The secondary outcome was the occurrence
of the side effect for example drowsiness, heartburn,
palpitation, and mouth dryness.
The data was analyzed by using statistics
program SPSS version 14.0. Data were analyzed using
Chi-square test or Fisher’s exact test and general linear
model in the form of repeated measurement adjust
for the co-variate by controlling the variation of the
difference nausea score and vomiting times before the
treatment in both groups (day 0). Student t-test was
used to test the coefficient of independent variable
(B). A p-value of less than 0.05 was considered significance
different.