The SPF of MS-E was about 1.1, indicating that MS also exhibited slight sunscreen ability due to its mesoporous structure. This is consistent with the UV absorption shown above. Besides, much higher SPF values of MCX-MS-E (12.6) than that of MCX-E (8.0) indicates a synergistic enhancement in the UV protection ability for MCX-MS-E. This is attributed to the combination of the sunscreen abilities of MCX and MS as well as to the good dispersion of MCX-MS in the sunscreen cream. Accordingly, the MCX encapsulated into the mesoporous silica matrix exhibited about 57% higher UV protection ability than the free MCX.