Abstract
Conclusion: The meta-analysis supported the proposition that the prevalence of gastroesophageal reflux disease (GERD) was
associated with laryngeal cancer, particularly in the hospital-based control group and diagnosed by esophagogastroduodenoscopy
(EGD) or esophageal pH monitoring. However, no significant association was found between GERD and pharyngeal
carcinoma. Objectives: A number of studies have been conducted to investigate the relationship between gastroesophageal
reflux and laryngeal or pharyngeal carcinoma