Conclusions
In summary, this study examines a relatively large sample
of stable patients with mild to very severe COPD.
The study identified a significant association between
anxiety, depression, or both and reduced HRQoL and
found that the magnitude of this association was modified
by working status, COPD severity, and the presence
of comorbidities. A better understanding of the influence
of psychological status on HRQoL at earlier stages
of COPD, including the identification of patients most
vulnerable to psychological impairment, is required.
This improved understanding could enable the application
of specific strategies in both clinical practice and
public health that seek to prevent further disability associated
with COPD.