Fugu (or puffer fish) is one of the most celebrated and notorious dishes in Japanese cuisine. Because it is so lethally poisonous if prepared incorrectly, chefs have to undergo rigorous training and be officially licensed to prepare it. The final test they undergo before being licensed, incidentally, is having to eat a piece of Fugu that they have prepared, which must focus the mind wonderfully. Even a tiny drop of toxin from the Fugu can leave unfortunate diners paralyzed and dying . It contains lethal amounts of the poison tetrodoxin in the organs, especially the liver and ovaries, and also the skin. The poison horrifyingly paralyzes the muscles while the victim stays fully conscious, and eventually dies from asphyxiation. There is no known antidote. Bon appetit.