Our data suggest that HPLC
diet alone cannot be accurately termed a “protein sparing” regimen. The absence of significant
changes in bone mineral density over the intervention for either group is reassuring. An increase
in urinary calcium excretion and a small decrease in bone mineral content were reported during
8 weeks of a carbohydrate restricted diet in adolescents, but these changes were reversed with
liberalization of carbohydrates. The absence of a comparison control group and the very small
sample size limits the generalizability of those findings