Cholesterol and sphingolipid-enriched membrane microdomains or platforms
Cholesterol levels double
Two types of lipid rafts
Caveolae: small, flask-shaped invaginations of the plasma membrane enriched in caveolin
Planar lipid rafts: found in neurons and enriched in flotillin
Caleolin and flotillin recruit signaling proteins
Signaling can be promoted or dampened