Stated in this way it is clear that the special tranfer are those about which there is the most uncertainty. It might indeed have “profound" implications for molecular biology”1 if any of there special tranfer could be shown to be general, or-if not in all cell-at least to be widely distributed. So far, however, there is no evidence for the frist two of there except in a cell infected with an RNA virus. In such a cell the central dogma demands that at least one of the frist two special tranfer should occur this statement, incidentally, shows the power of the central dogma in making theoretical predictions. Nor, as I have indicated is there any good theoretical reason why the tranfer RNA-DNA should not sometimes be used. I have never suggested that it cannot occur, nor, as far as I know, have any of my colleagues.
Although the details of the classification proposed here are plausible, our knowledge of molecular biology, even in one cell-let alone for all the organism in nature is still far too incomplete to allow us to assert dogmatically that it is correct. (There is, for example, the problem of the chemical nature of the agent of the disease scrapie : see the articles by Gibbons and Hunter and Griffith. Nevertheless we know enough to say that a non-vial) example showing that the classification was wrong could be an important discovery. It would certainly be of great interest to find a cell (as opposed to a virus) which hAd RNA as its genetic material and no DNA or a cell which used single stranded DNA as messenger than RNA.
Stated in this way it is clear that the special tranfer are those about which there is the most uncertainty. It might indeed have “profound" implications for molecular biology”1 if any of there special tranfer could be shown to be general, or-if not in all cell-at least to be widely distributed. So far, however, there is no evidence for the frist two of there except in a cell infected with an RNA virus. In such a cell the central dogma demands that at least one of the frist two special tranfer should occur this statement, incidentally, shows the power of the central dogma in making theoretical predictions. Nor, as I have indicated is there any good theoretical reason why the tranfer RNA-DNA should not sometimes be used. I have never suggested that it cannot occur, nor, as far as I know, have any of my colleagues.Although the details of the classification proposed here are plausible, our knowledge of molecular biology, even in one cell-let alone for all the organism in nature is still far too incomplete to allow us to assert dogmatically that it is correct. (There is, for example, the problem of the chemical nature of the agent of the disease scrapie : see the articles by Gibbons and Hunter and Griffith. Nevertheless we know enough to say that a non-vial) example showing that the classification was wrong could be an important discovery. It would certainly be of great interest to find a cell (as opposed to a virus) which hAd RNA as its genetic material and no DNA or a cell which used single stranded DNA as messenger than RNA.
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