Introduction to Clinical Health Problem: Pathophysiology
Incidence
• The estimated incidence of ovarian cancer in 2012 is 22,280 with 15,500 deaths.1,2
o It is the 5th leading cause of cancer deaths in women, responsible for 3% of all cancers in women.
o It is also the deadliest gynecologic cancer causing more deaths than cervical and endometrial cancers combined.
• Epithelial cancers account for more than 90% of ovarian cancers; germ cell or sex-cord stromal are the majority of nonepithelial ovarian cancers.2
• The primary method of metastasis is by direct extension and exfoliation of cells that implant along surfaces of the peritoneal cavity.
• The cancer antigen-125 (CA-125) is a tumor marker that may be used for monitoring ovarian cancer, but it is not a screening tool when used by itself.
• Ovarian cancers recur 80% of the time.
• Stage is the most important prognostic indicator for 5-year survival2:
o Stage I, 85%
o Stage II, 60%
o Stage III, 30%
o Stage IV, 18%
• Other prognostic indicators are age, performance status, and histologic tumor type and grade.
Introduction to Clinical Health Problem: PathophysiologyIncidence• The estimated incidence of ovarian cancer in 2012 is 22,280 with 15,500 deaths.1,2o It is the 5th leading cause of cancer deaths in women, responsible for 3% of all cancers in women.o It is also the deadliest gynecologic cancer causing more deaths than cervical and endometrial cancers combined.• Epithelial cancers account for more than 90% of ovarian cancers; germ cell or sex-cord stromal are the majority of nonepithelial ovarian cancers.2• The primary method of metastasis is by direct extension and exfoliation of cells that implant along surfaces of the peritoneal cavity.• The cancer antigen-125 (CA-125) is a tumor marker that may be used for monitoring ovarian cancer, but it is not a screening tool when used by itself.• Ovarian cancers recur 80% of the time.• Stage is the most important prognostic indicator for 5-year survival2:o Stage I, 85%o Stage II, 60%o Stage III, 30%o Stage IV, 18%• Other prognostic indicators are age, performance status, and histologic tumor type and grade.
การแปล กรุณารอสักครู่..

Introduction to Clinical Health Problem: Pathophysiology
Incidence
• The estimated incidence of ovarian cancer in 2012 is 22,280 with 15,500 deaths.1,2
o It is the 5th leading cause of cancer deaths in women, responsible for 3% of all cancers in women.
o It is also the deadliest gynecologic cancer causing more deaths than cervical and endometrial cancers combined.
• Epithelial cancers account for more than 90% of ovarian cancers; germ cell or sex-cord stromal are the majority of nonepithelial ovarian cancers.2
• The primary method of metastasis is by direct extension and exfoliation of cells that implant along surfaces of the peritoneal cavity.
• The cancer antigen-125 (CA-125) is a tumor marker that may be used for monitoring ovarian cancer, but it is not a screening tool when used by itself.
• Ovarian cancers recur 80% of the time.
• Stage is the most important prognostic indicator for 5-year survival2:
o Stage I, 85%
o Stage II, 60%
o Stage III, 30%
o Stage IV, 18%
• Other prognostic indicators are age, performance status, and histologic tumor type and grade.
การแปล กรุณารอสักครู่..
