It is widely accepted that cell cycle regulatory genes are specifically regulated by auxin and NO during LRI (De Smet et al., 2010 and Correa-Aragunde et al., 2006). It was further confirmed cell cycle-dependent alterations by H2S in animals (Baskar and Bian, 2011). Our previous study suggested that the H2S promoted cucumber adventitious root formation by the modulation of DNAJ-1 and CDPK1/5 genes ( Lin et al., 2012). Therefore, the above link prompted us to further investigate the DES-mediated molecular mechanism leading to lateral root development triggered by NaHS