UVC-Induced CellularLesions
TwomajorUV-induced lesion mechanisms in cells form CPDs
and/or 6–4 photoproducts(6–4PPs) and their valenceisomers. These are the principal lesions leading to mutagenesis.
The formation of 6–4PPs also may result in changes in cell
metabolism as they can inhibitor induce other combined
cytotoxic effects.