H2 did not enhance the sperm swimming speed
(Figure 3), indicating that H2 did not hyperactivate sperm.
Hyperactivation is characterized by a more energetic and
less symmetric beat of sperm flagella and can be achieved
in vitro by seminal plasma removal and incubation of
sperm in capacitating medium. However, several reagents,
including caffeine, which can stimulate sperm movement,
have no effect on sperm velocity [30]. On the other hand,
exogenous pyruvate accelerates glycolysis, and stimulates
motility and hyperactivation with an increase in
intracellular ATP levels [28]. It has been reported that
glucose-derived ATP during capacitation involves hyperactivation
[31], indicating that H2 treatment does
not affect glycolysis.
H2 did not enhance the sperm swimming speed(Figure 3), indicating that H2 did not hyperactivate sperm.Hyperactivation is characterized by a more energetic andless symmetric beat of sperm flagella and can be achievedin vitro by seminal plasma removal and incubation ofsperm in capacitating medium. However, several reagents,including caffeine, which can stimulate sperm movement,have no effect on sperm velocity [30]. On the other hand,exogenous pyruvate accelerates glycolysis, and stimulatesmotility and hyperactivation with an increase inintracellular ATP levels [28]. It has been reported thatglucose-derived ATP during capacitation involves hyperactivation[31], indicating that H2 treatment doesnot affect glycolysis.
การแปล กรุณารอสักครู่..
