Therefore, an approach is required aimed at the
development of new ways to create water-insoluble microparticles,
with reduced porosity and retarded release of entrapped
substances. This can be achieved by combining alginate with complementary
plant derived biopolymers, such as chitosan, carrageenan
or synthetic polymers, for example PVA or Poly-L-Lysine.
The combination of Ca2+ alginate with other carrier materials
may serve as a successful strategy to increase the gel mechanical
properties and reduce its permeability, but also to combine the
favourable properties of both polymers, improving their ability as
carriers for achieving a specific drug delivery