3-Aminocoumarin derivatives have been found to also possess a wide range of biological activities,
including CNS depressant, [32] antibacterial, [33] antiallergic [34] and insect-growth regulatory
effects [35]. Medicinal metal complexes have become an interesting research area since the discovery
of cisplatin [36]. Since then, many complexes have been synthesized and tested on a number of
biological systems. Copper complexes are known to have a broad spectrum of biological action [37].
The preparation of 3-aminocoumarin and its use as a ligand for the formation of Cr(III), Ni(II), and
Cu(II) complexes, is presented in this study. The chemical structures of the newly synthesized
complexes were confirmed. The microbial activities of all synthesized compounds and their in vitro
antioxidant activities were also investigated