discussion
the use of plants and plant products for wound healing has a long history. Especially in countries like India, China and Iran that there is more interest in traditional medicine, valuable information is available on using unknown plants for treating wounds (Feringa et al., 2011). However, little scientific research has been done to prove their benefits. Today, the use of various herbal extracts that have a long history of use in traditional medicine, has also been considered in accelerating skin wound healing (Bhatia et al., 2010; Li et al., 2012). Extensive studies suggest that grape seed extract has health benefits in many ways as a result of its antioxidant effect.