Estrogen plays many important regulatory functions in phy-
siological processes in females, such as the development and regulation of reproductive tissue
functions, management of en- ergy, maintenance of body weight and functioning of bones. The natural
decline in the estrogen level during menopause con- tributes to the increased risk of several
diseases, including obesity, cardiovascular diseases and osteoporosis (Nilsson and Gustafsson,
2002). While the administration of estrogen to women can lower the risk as well as prevent or
alleviate these symptoms, the pos- sible carcinogenic effects of estrogen administration have
limited its long-term usage (Beral et al., 2002; Lethaby et al., 2004). Many studies are,
therefore, focused on searching for safer alternatives for post-menopausal treatment, and in particular forphytoestrogens.
Estrogen plays many important regulatory functions in phy-siological processes in females, such as the development and regulation of reproductive tissue functions, management of en- ergy, maintenance of body weight and functioning of bones. The natural decline in the estrogen level during menopause con- tributes to the increased risk of several diseases, including obesity, cardiovascular diseases and osteoporosis (Nilsson and Gustafsson, 2002). While the administration of estrogen to women can lower the risk as well as prevent or alleviate these symptoms, the pos- sible carcinogenic effects of estrogen administration have limited its long-term usage (Beral et al., 2002; Lethaby et al., 2004). Many studies are, therefore, focused on searching for safer alternatives for post-menopausal treatment, and in particular forphytoestrogens.
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