Recently, the National Science, Technology and Innovation (STI) Act (2008) was enacted to provide a framework for public and private sector institutions to strengthen the nation’s STI capabilities. Capabilities to be strengthend include S&T manpower, S&T infrastructure, public awareness on S&T, and S&T management and administration systems. Compliance with this STI Basic Law requires management mechanism for implement. Monitoring and evaluation systems, and flexibility of rolling improvement. According to the law, a new supra-ministerial structure-the National Science, Technology and Innovation Policy Committee, has been found, to be chaired by the prime minister. Members of the Policy Committee include ministers from key ministries relevant to science, technology and innovation, together with respected resource persons. To execute National and innovation, together with respected resource persons. To execute National Science Technology and Innovation Act(2008), National Science Technology and Innovation Policy Office (or STI) was established. The office is committee to assist the country in moving towards knowledge-based economy in order to promote the country’s capacity and strength. The science technology and innovation strategic plan and policy recommendations provided to the government by the office are expected to improve the country’s competitiveness and enhance socio-economic sustainability. STI principally works with the industry, government, academics, and local community sectors in undertaking its activities. Collaborative networking is an essential part of the office and is emphasized by the creation and promotion of active collaboration through strong linkages and exchange programs with local, overseas, and international organization. Nonetheless, it is still premature to evaluate the effectiveness of STI.