The techniques reported here are a mixture of the easily accessible
(fluorescence and CD) and the highly specialized (SPR and mass
spectrometry). This distinction is an important one in terms of the
mass screening of protein-nanoparticle interactions to characterize
nanoparticles in terms of their protein corona. In order for this to
become feasible for the screening/characterization of the 30 000
nanoparticles that are claimed to be in the industrial pipeline
worldwide, the experimental techniques need to be robust, easily
accessible, and high throughput (where possible). We highlight here
another approach that could potentially contribute to large-scale
screening of nanoparticle-protein interactions, namely zeta potential