The purpose of this research is the development of the skills of observation by inquiry method (5E) group learning, science title classification of plants and reproduction of animals and propagation.For prathomsuksa with a population is prathomsuksa 5 number 10 people during the academic year 2557 1 which comes from a purposive sampling. The instruments used in the study include is learn a lesson plan, the inquir (5E), 2 lesson plans is it classification of plants and reproduction of animals and propagation. And tests before and after learning.