Cardiovascular effects
Like other beta2-adrenergic agonists, olodaterol may produce a clinically significant cardiovascular
effect in some patients as measured by increases in pulse rate, blood pressure, and/or symptoms. In
case such effects occur, treatment may need to be discontinued. In addition, beta-adrenergic agonists
have been reported to produce electrocardiogram (ECG) changes, such as flattening of the T wave and
ST segment depression, although the clinical significance of these observations is unknown.