Risk was elevated regardless of when
in the past the heavy consumption had occurred; ORs
ranged from 2 to 2.6 for heavy drinking in the past 10, 20,
or 30 years (data not shown). When analyses were
restricted to the heaviest drinkers, results showed that risk
increased with increasing decades of heavy consumption
([21 drinks/week p-trend = 0.02, [35 drinks/week
p-trend = 0.01, Table 2).