Taking advantage of the latest advancements in the field of genomic, transcriptomic, proteomic, and metabolomic techniques, plant biologists are focusing on the development of a complete profile of genes, proteins, and metabolites responsible for different mechanisms of salinity tolerance in different plant species. However, there is lack of the integration of information from genomic, transcriptomic, proteomic, and metabolomics studies, and the combined approach is essential for the determination of the key pathways or processes controlling salinity tolerance