It is not difficult to see what the authors are required to do in order for their paper to be considered for publication in Nature. By “stating ... why the conclusion is an important scientific advance’’, the authors need to be able to convince the editor of Nature that the conclusion presented by the paper is worth publishing! To do that, they need, above all, to be able to explain clearly what the research conclusion is. As instructed by the guideline, authors are required to summarize the significance of their research in just 100 words. This means that they have to be very clear about the conclusion of their research in order to highlight its significance. Furthermore, they need to be able to make the research conclusion understandable by a wide range of readers. This means that they must make the steps leading to the research conclusion not only easy to understand but also logically convincing, so that even non-specialists could be persuaded. Accordingly, having a clear research conclusion and a convincing logical argument for the conclusion are necessary for an academic paper to get published in Nature.