The purpose of this study was to evaluate a substrate formula- tion containing SSH to obtain a compost capable to support a complete growth cycle of A. blazei with acceptable yield perfor- mance; also examine the use of different types of substrate containers and substrate masses and deep into the lignocellulose biodegradation in order to unequivocally decide if lignin is used efficiently as a nutrient by A. blazei, as well as to know the evolution and interrelation of the cellulose and hemicellulose. The results show an adequate compost for the cultivation of this mushroom with similar yields to those obtained with other commonly employed materials, and with yields higher when using poly- ethylene bags rather than trays as containers. It is also confirmed the lignin degradation by this mushroom during its cultivation.