1. Introduction
The inflammation is classified into acute inflammation that is a
limited beneficial process, particularly in response to infectious
pathogens, and chronic inflammation that is an undesirable
persistent phenomenon that can lead to the development of
inflammatory diseases. Inflammation is fundamentally a protective
response to foreign and the noxious stimuli and serves to
eliminate the initial cause of cell injury as well as the necrotic
cells resulting from the original insult. The inflammatory
response is constituted by an innate system of cellular and
humoral responses following insult. It consists of three stages
which are: injury, regeneration and repair, and serves to destroy,
dilute or wall off the injurious agent, and it sets into motion a
series of events that try to heal and reconstitute the damaged
tissue. Pain is a common symptom of various inflammatory
diseases and sometimes the patients need pharmacological