The
implementation of this system could maximize the in vitro
production of embryos by providing a large number of
oocytes that are homogeneous and meiotically competent for
several biotechnologies such as in vitro fertilization, cloning
and transgenesis. In the rodent, in vitro follicle growth within
several culture systems has resulted in live births (O’ Brien et
al. 2003; Xu et al. 2006) and efforts are also currently in
progress in nonhuman primates and in humans (Xu et al.
2009a, b).