Platelets are produced from the cytoplasmic fragmentation of
megakaryocytes as anucleate cells [23–26]. Bone marrow stromal
cells get infected as a result of dengue virus infection, affecting
normal function of bone marrow that leads to low production of
platelets [27–29]. Destruction of platelets within the blood stream
may probably be due to carotene deficiency causing dryness of a
cellular wall, resulting an ultimate cell death. In normal condition
there are varieties of cytoplasmic structures inside the platelet.
These structures includes lysosomes and two types of granules
i.e. electron dense granules and -granules actin (protein) uniformly distributed throughout and an irregular internal network of
canaliculi through which the granules content comes to the platelet surface