needs to be avoided
as carries up to 50% mortality
and is highest for late
re‑intubations partly due to different severity of disease
and of underlying comorbidities at the time of extubation,
but also contributed by clinical deterioration directly
generated by extubation failure and respiratory distress
of re‑intubation, and later by the issues of prolongation
of MV. As organ failures have been shown to worsen
after re‑intubation with increase in mortality, it is prudent
to prevent it as far as possible by refining decisions to
extubate and postextubation management. Hence, to
make extubation in COPD a success, there is a need to
optimize preextubation strategies as well as postextubation
interventions so as to prevent re‑intubation.