Discussion
To our knowledge, the present study is the first to report a significant increase in blood EPA and DHA levels, as Omega-3 Index, in a group of healthy indi- viduals who were regular consumers of fish oil sup- plements at baseline. Maximizing the response to omega-3 supplementation may be a prudent clinical target for the reduction of certain risk factors, and Omega-3 Index may be an appropriate biomarker for assessing and monitoring the effectiveness of omega-3 supplementation.
An increase in the Omega-3 Index has been correlated with reductions in cardiovascular risk factors, and low